Development of HPLC methods for the determination of water-soluble vitamins in pharmaceuticals and fortified food products

Liquid chromatography with isotope-dilution mass spectrometry for determination of water-soluble vitamins in foods.

Vitamins are essential for improving and maintaining human health, and the main source of vitamins is the diet. Measurement of the quantities of water-soluble vitamins in common food materials is important to understand the impact of vitamin intake on human health, and also to provide necessary information for regulators to determine adequate intakes. Liquid chromatography (LC) and mass spectro...

Development of Analytical Methods for Determination of Water Soluble Vitamins in Functional Food Products

اندازه‌گیری و مقایسه مقدار اسیدفولیک در آردهای غنی‌شده و نان به روش کروماتوگرافی مایع با کارایی بالا (HPLC) در شهر ارومیه

Background & Aims: Folate has been identified as one of the most important water-soluble B vitamins for normal metabolic function and it is essential for normal human cell division and cell growth. Since humans cannot synthesize folates, they must obtain from dietary sources. The most important dietary sources of folates are fortified foods, and cereal products with folate content of 50-20...

Determination of Vitamin D3 in Fortified Iranian Flat Bread (Taftoon) Using High-Performance Liquid Chromatography

Background and Objectives: : Vitamin D3 measurement in food and fortified food matrixes is usually interrupted by several variables. This study aimed to elaborate a specific vitamin D3 quantification method for fortified Taftoon bread considering different influential variables in each step of measurement. Materials and Methods: Dough was fortified with (4μg/100g) and the sta...

Development and validation of a fast, simple and specific stability indicating RP-HPLC method for determination of Dexpanthenol in eye gel formulation.

AIn this study a simple and reliable stability-indicating RP-HPLC method was developed and validated for analysis of Dexpanthenol in an artificial tear formulation. The chromatographic separation was performed on a HPLC C18 column (25.0 cm  4.6 mm, 5 m) using a mixture of 0.037 M monobasic potassium phosphate in water (adjusted with 0.1% (v/v) phosphoric acid to a pH of 3.2) and methanol (90:...